Charlotte’s Web is a cannabis strain with high cannabidiol (CBD) used to treat children with epilepsy.

The endocannabinoids anandamide and 2-AG act as retrograde neurotransmitters in synaptic plasticity and memory formation, anxiety and pain.

THC, CBD and other cannabinoids found in marihuana act through CB1, CB2 and GPR55 receptors.

Neurons process information as excitatory and inhibitory postsynaptic potentials in dendrites that generate action potentials in the axon.

Since there is no consciousness after death, we experience nothing, so there is nothing to fear.

Mind-fucking in BDSM presents unique challenges to avoid breaking consent, trauma, and inducing learned helplessness.

Denial of free will is based on religious or mystical ideas and can have dire consequences by making it ethical to control the mind.

In transgenic mice, fluorescent reporter genes, optogenetics and DREADD are used to manipulate the function of cells.

Pain is a sensation that is not always unpleasant, while suffering is a state of being based on emotions, values and meaning.

Masochist pain activates brain areas involved in empathy, emotion and consciousness, but not in addiction.

Neuroscience explains consciousness as hierarchical properties of the mind.

This coveted state of bliss and euphoria in BDSM scenes may actually be different mental states In the BDSM community, submissive space...