Figging is inserting ginger in the anus or the vagina to produce a burning erotic sensation

Sadism is the consensual infliction of physical or emotional pain while cruelty is to make people suffer for an ulterior goal.

The runner’s high is an example of endorphin rush, but it is unclear if it is caused by endorphins or endocannabinoids.

Porn is not addictive. It induces short increases of dopamine and not the sustained ones produced by cocaine and opioids.

Unique characteristics of the human brain let us experience suffering as extending to the past and the future, and to others.

Mutations that increase the endocannabinoid anandamide decreased pain, but did not eliminate as completely as mutations in Nav1.7

The endocannabinoids anandamide and 2-AG act as retrograde neurotransmitters in synaptic plasticity and memory formation, anxiety and pain.

Pain is a sensation that is not always unpleasant, while suffering is a state of being based on emotions, values and meaning.

Masochist pain activates brain areas involved in empathy, emotion and consciousness, but not in addiction.

In BDSM, sub space is an altered state of consciousness mediated by adrenaline and endorphins.